Inyline™ Solution, created by Lipotec, brings a novel approach to the cosmetic treatment of expression wrinkles. There are two main strategies to minimize muscle contraction: •PRE-SYNAPTIC strategy, which involves different mechanisms that restrain or inhibit the release of the neurotransmitter (acetylcholine) from the motor neuron. The most known example of this is Botulinum Toxin, which inhibits ACh release into the synapse from the vesicles in such a dramatic way that it paralysis the muscle. Examples of well-known peptide products that utilize this method of action include Argireline, SNAP-8 and SNAP-7 by Lipotec. These are safer, cheaper and milder alternatives to Botulinum Toxin. •POST-SYNAPTIC strategy, which avoids or diminishes the ligand (ACh) – receptor (AChR) binding responsible for the formation of the action potential. In this strategy, although the neurotransmitter is released into the synapse, the post-synaptic apparatus does not respond to it.
Topical Collagen In order to appreciate the potential importance of Pseudo collagen to cosmetic formulators, an understanding of the role of soluble collagen is required. Soluble collagen provides an important function in the skin matrix, not only for its structural properties, but also for its ability to help hold moisture in the dermis. Collagen fibrils provide the rigid dermal framework around which the moisture binding proteoglycan structure is woven. Elastin fibrils supply the whole structure due to their elasticity. The appearance of the skin is directly proportional to its ability to bind water. Upon aging, the collagen and elastin content in connective tissue reduces with an accompanying decrease in ability to retain moisture. The skin becomes thinner, takes on an aged appearance and often develops wrinkles. Hydrolyzed, bovine and marine Collagen, like soluble collagen, affords excellent moisturizing properties resulting in smoothing fine lines and wrinkles; improving skin tone and texture, increasing elasticity, decreasing the appearance of cellulite, crow's feet and gaining suppleness and radiance.
In short our peptides effectively rejuvenate the skin through rapid cell turnover; produce new collagen; strengthen capillaries; increase micro-circulation; reduce muscle contractions and increase cellular communication. The results are: improved epidermal nourishment; improved skin compactness; reduced lines, wrinkles and crows feet, improved structural integrity, improved skin tone, increased skin firmness, and improved elasticity. View our anti aging skin care products at our Pure Radiance Skin Care Shop for full details, ingredient benefits and to make your purchase.
Syn®-Hycan is a tripeptide offering a number of skin care benefits. It increases the padding between skin cells, fortifies collagen fibrils, and visibly remodels the skin for a firmer more youthful look. Syn-Hycan boosts hyaluronan production in the skin. It increases the expression of Decorin (a pericellular matrix protein which is a component of connective tissue, binds to Type I collagen fibrils, and plays a role in matrix assembly) and Lumican (reorganizes collagen fibril regulation, epithelial cell migration and tissue repair). The function of Syn-Hycan will provide visible skin care remodeling of facial and neck contours. Skin will look firmer and more youthful. Used in our Ultra Lift Day Cream.
Similar to copper peptides, Matrixyl™ 3000 stimulates the lower layers of the skin thus accelerating and regenerating the skin. It simulates the "matrix" layers in the skin, primarily collage and fibronectin. When stimulated, the skin produces more collagen. Loss of collagen is what leads to thinning and wrinkling of your skin. Matrixyl™ 3000 helps to counteract this natural part of the aging process. Used in our Miracle Multiple Peptide Serum.
Leuphasyl® treats expression lines, forehead wrinkles and crows feet in anti aging skin care products. Clinical trials were performed showing immediate line smoothing & tightening; where the severity of wrinkles decreased 17% after 15 days, and up to 32% after 28 days. Leuphasyl®’s mechanism mimics in vitro the natural mechanism of enkephalins. It couples to the receptor on the outside of the nerve cells and a conformational change initiates a cascade inside the neuron that results in a decrease of its excitability (the nerve cell’s activity is “turned down”) and the release of acetylcholine is modulated. Muscle contraction will be relaxed and therefore, expression wrinkles will be diminished. It reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead, mouth and around the eyes.
Pepha®-Tight is a highly purified produced extract from the Nannochloropsis oculata. It functions as a skin tightener containing vitamin C, B12 and E. Clinical studies have proven immediate tightening to the skin, and have been shown to protect human fibroblasts from oxidative stress, simultaneously increasing the formation of collagen-l. It is rich in amino acids and these make it a powerful antioxidant; promoting a long term tightening effect through the strengthening of the skins connective tissue. Used in our Time Freeze Eye Cream and our Reverse and Repair Night Creams.
TEGO® Pep 4-17 is a pure tetra peptide with anti aging properties based on the skin's own structures. It activates collagen production and therefore stimulates dermal filling, repair and renewal mechanisms of the skin. It leads to an increased elasticity and a decreased volume of wrinkles and fine lines. Clinical testing on skin care creams showed a 25% improvement in skin roughness and depth of fine and coarse wrinkles. It is an ideal active ingredient to prevent and minimize the appearance of skin aging based on its collagen boosting activity out performing the current market standard (Matrixyl). Used in our Ultra Lift Day Cream.
Syn®-Coll is a peptide designed to stimulate the skin's natural mechanism to produce collagen. It is based on a small peptide developed to reduce any type of wrinkles. It stimulates collagen synthesis, actively removes any type of wrinkle, additional skin firming and moisturizing properties, clinically proven to be safe and effective as part of a skin care routine within anti aging skin products. Skin aging and in particular chronic UV exposure, leads to degenerative changes in skin. This is characterized by distinct alterations in the composition of the dermal extra cellular matrix (ECM). The consequences are manifold such as increased skin fragility, leathery skin appearance and formation of wrinkles. Collagen represents the main component of the ECM of the dermal connective tissue. Thrombospondin I (TSP) is a multi functional protein that activates the latent but biologically inactive form of TGF (Tissue Growth Factor). TGF is known as the key element in the synthesis of collagen and binds to a particular sequence in the TSP molecule. This sequence is known as ARG-PHE-LYS. As a molecule able to activate TGF, SYN®-COLL is considered to be an ideal aqueous based peptide. It contains a unique sequence designed to mimic the human body's own mechanism to product collagen via TGF. Accordingly, SYN®-COLL actively compensates for any collagen deficit, thus making the skin look younger. Used in our Miracle Multiple Peptide Serum and Reverse and Repair Night Cream.
Syn®-Tacks provides structural and functional integrity to our skin, but that functionality starts to decline around the age of 30. This decline in functionality proceeds and is even accelerated by external and environmental influences such as UV light, resulting in decreasing skin compactness, elasticity and a lack of skin firmness. Tacks Tacks Functionality: Improved structural integrity; epidermal nourishment; molecular communication within the skin; improved skin compactness; skin tonicity; reduced wrinkles; improved skin firmness. An ideal addition for anti skin care products, moisturizers, skin care. Used in our Miracle Multiple Peptide Serum.
Trylagen® is a combination of active peptides and proteins that can fight the processes that affect the quantity and quality of collagen. It acts on collagen via 3 main functions: Collagen boosting, organization and protection. Collagen boosting: Trylagen® boost the synthesis of collagen types I, III and IV, helping to compensate for our decreased production as we age. Collagen organization: Trylagen® controls collagen fibril dimensions by changing their diameter, and spacing them regularly. This provides a better cohesion and stabilization of collagen fibers, and gives suppleness to the skin. Collagen protection: Trylagen® inhibits the production of human MMP-2 and MMP-3, therefore avoiding excessive collagen damage. It also protects skin from the loss of elasticity. Trylagen® helps maintain our collagen quantity and quality, and this is macroscopically translated in a significant anti aging effect. Used in our Lift and Repair Eye Gel.
Matrixyl™ 3000 Studies have proven a decrease in skin roughness, a reduction in wrinkle volume, a decrease in wrinkle depth on the face and neck days of use, including an increase in skin thickness. In further clinical studies, Matrixyl™ 3000 was show to increase overall collagen synthesis by up to 71%, increase collagen IV synthesis by up to 64%, increase hyaluronic acid synthesis by up to 67%. Deep wrinkles were reduced by half and some smaller wrinkles and fine lines faded away completely. The result was fewer wrinkles and younger looking skin. It is well tolerated and no side effects have been reported.
Snap-8 is just one of the amazing ingredients that Pure Radiance natural skin care anti aging pproducts include. It is considered a non-pharmaceutical, safer and a more reasonably priced topical alternative to Botox in anti aging skin care products. In clinical studies, the severity of wrinkles around the eyes decreased up to 63.13%. It reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes. It inhibits SNARE complex formation (muscle contraction is attenuated), resulting in the reduction of the degree of existing facial wrinkles and demonstrated effectiveness against preventing the formation of lines and wrinkles with regular use as part of your skin care routine. Used in our Time Freeze Eye Cream.
Argireline NP Dr. Oz recently praised the use of Argireline in natural skin care products and eye serums and wrinkle creams! Any ingredient that earns the praise of Dr. Oz is a must have ingredient! Although the effects cannot be compared to the injected effects of Botox, when Argireline is applied topically to the skin, the effects of aging are drastically reduced- Argireline is considered by experts to be one of the best non- pharmaceutical, safer and cheaper topical alternatives to Botox. Argireline is a peptide that inhibits SNARE complex formation, resulting in the reduction of the degree of existing facial wrinkles and demonstrated effectiveness against their development with regular use as part of your skin care routine. In clinical studies of twice-a-day skin care treatment, Argireline decreased the severity of wrinkles around the eyes up to 17% after 15 days and 30% following 30 days of treatment. Pure Radiance Natural Skin Care Peptides are meant to be powerful! Used in our Miracle Multiple Peptide Serum.
Peptides occur naturally in the body and are composed of amino acids. Amino acids are the basic building blocks of proteins and many other different types of organic molecules. Peptides are frequently created by the digestion of proteins in the body, and are readily and rapidly absorbed by the bloodstream. The ones used in natural skin care, communicate and direct the skin cells to behave in a certain way, such as producing more collagen or thickening the skin. When peptides are added to organic ingredients in creams, serums or other products, the formula becomes increasingly powerful and rejuvenation and cell turnover is rapidly enhanced. For this reason, peptides are particularly effective as anti aging skin care ingredients.
Peptides are used in only premium anti aging skin care products due to their high cost, complexity and effectiveness. Peptides and Organics are our passion and we are pleased to offer a variety of multiple peptides at maximum percentages in our anti aging skin care products and targeted anti aging treatments. We have carefully selected the peptides that we use. Our products are formulated to not only rejuvenate the skin through rapid cell turnover, they produce new collagen, strengthen capillaries and increase micro-circulation, reduce muscle contractions, and increase cellular communication; resulting in improved epidermal nourishment, skin compactness, reduced lines, wrinkles and crows feet, improved structural integrity and skin tonicity, firmness and elasticity.
We are passionate about Peptides and encourage all of our customers to gain knowledge of the ingredients we use and the incredible results they produce. Read further to discover the wonderful world of peptides and their benefits. See our Shop Page for individual product ingredients and benefits. All anti aging skin care products contain multiple peptides.